Human SH2D4A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SH2D4A
Locus ID	63898
Kit Components	GA111904G1, SH2D4A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111904G2, SH2D4A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111904G3, SH2D4A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001174159, NM_001174160, NM_022071, NM_001363111, NR_156444, NM_001363110
Synonyms	PPP1R38; SH2A
Summary	Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.[UniProtKB/Swiss-Prot Function]

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