Human PLEKHA1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLEKHA1
Locus ID	59338
Kit Components	GA111824G1, PLEKHA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111824G2, PLEKHA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111824G3, PLEKHA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001001974, NM_001195608, NM_001330178, NM_021622
Synonyms	TAPP1
Summary	This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010]

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