Human MEAK7 (TLDC1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MEAK7
Locus ID	57707
Kit Components	GA111701G1, MEAK7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111701G2, MEAK7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111701G3, MEAK7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020947
Synonyms	KIAA1609
Summary	Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration (PubMed:29750193). Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome (PubMed:29750193).[UniProtKB/Swiss-Prot Function]

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