Human ARHGAP23 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGAP23
Locus ID	57636
Kit Components	GA111650G1, ARHGAP23 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111650G2, ARHGAP23 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111650G3, ARHGAP23 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199417, NM_020876
Synonyms	KIAA1501
Summary	The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008]

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