Human SH3MD2 (SH3RF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SH3RF1
Locus ID	57630
Kit Components	GA111646G1, SH3MD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111646G2, SH3MD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111646G3, SH3MD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020870
Synonyms	POSH; RNF142; SH3MD2
Summary	This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. [provided by RefSeq, Jul 2008]

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