Human RELCH activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RELCH
Locus ID	57614
Kit Components	GA111634G1, RELCH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111634G2, RELCH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111634G3, RELCH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001346229, NM_001346230, NM_001346231, NM_001346232, NM_001346233, NM_001346234, NM_001346235, NM_020854, NR_144403, NR_144404, NR_144405, NR_144406, NR_144407, NR_144408, NR_144409, NR_144410, NR_144411, NR_144412
Synonyms	HsT885; HsT3308
Summary	Regulates intracellular cholesterol distribution from recycling endosomes to the trans-Golgi network through interactions with RAB11 and OSBP (PubMed:29514919). Functions in membrane tethering and promotes OSBP-mediated cholesterol transfer between RAB11-bound recycling endosomes and OSBP-bound Golgi-like membranes (PubMed:29514919).[UniProtKB/Swiss-Prot Function]

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