Human KIAA1432 (RIC1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RIC1
Locus ID	57589
Kit Components	GA111614G1, KIAA1432 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111614G2, KIAA1432 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111614G3, KIAA1432 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001135920, NM_001206557, NM_020829
Synonyms	bA207C16.1; CIP150; KIAA1432
Summary	The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1.[UniProtKB/Swiss-Prot Function]

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