Human Dedicator of cytokinesis protein 6 (DOCK6) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DOCK6
Locus ID	57572
Kit Components	GA111599G1, Dedicator of cytokinesis protein 6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111599G2, Dedicator of cytokinesis protein 6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111599G3, Dedicator of cytokinesis protein 6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020812, NM_001367830
Synonyms	AOS2; ZIR1
Summary	This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2. [provided by RefSeq, Dec 2011]

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