Human TRMT5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRMT5
Locus ID	57570
Kit Components	GA111597G1, TRMT5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111597G2, TRMT5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111597G3, TRMT5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020810, NM_001350253, NM_001350254
Synonyms	COXPD26; KIAA1393; TRM5
Summary	tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]).[supplied by OMIM, Mar 2008]

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