Human FAM62B (ESYT2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ESYT2
Locus ID	57488
Kit Components	GA111530G1, FAM62B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111530G2, FAM62B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111530G3, FAM62B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020728, NM_001367773
Synonyms	CHR2SYT; E-Syt2; FAM62B
Summary	Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex.[UniProtKB/Swiss-Prot Function]

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