Human ABHD6 activation kit by CRISPRa
CAT#: GA111483
ABHD6 CRISPRa kit - CRISPR gene activation of human abhydrolase domain containing 6
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | ABHD6 |
Locus ID | 57406 |
Kit Components | GA111483G1, ABHD6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111483G2, ABHD6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111483G3, ABHD6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_001320126, NM_020676 |
Summary | Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol (PubMed:22969151). Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways (By similarity). Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity). Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism (PubMed:26491015). BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting (PubMed:26491015).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN400915 | ABHD6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |