Human ZNF304 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZNF304
Locus ID	57343
Kit Components	GA111471G1, ZNF304 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111471G2, ZNF304 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111471G3, ZNF304 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290318, NM_001290319, NM_020657, NM_001329456
Summary	This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein functions as a transcriptional repressor that recruits a corepressor complex to stimulate promoter hypermethylation and transcriptional silencing of target genes. Expression of this gene is upregulated in colorectal, ovarian and breast cancer, and this gene may promote cancer cell survival, growth and invasion. [provided by RefSeq, Jul 2016]

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