Human SPINLW1 (EPPIN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EPPIN
Locus ID	57119
Kit Components	GA111385G1, SPINLW1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111385G2, SPINLW1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111385G3, SPINLW1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001302861, NM_020398, NM_181502
Synonyms	CT71; CT72; dJ461P17.2; SPINLW1; WAP7; WFDC7
Summary	This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility and exhibits antimicrobial activity against E. coli, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

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