Human ANKS1B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ANKS1B
Locus ID	56899
Kit Components	GA111252G1, ANKS1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111252G2, ANKS1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111252G3, ANKS1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001204065, NM_001204066, NM_001204067, NM_001204068, NM_001204069, NM_001204070, NM_001204079, NM_001204080, NM_001204081, NM_020140, NM_152788, NM_181670, NM_001352185, NM_001352186, NM_001352187, NM_001352188, NM_001352189, NM_001352190, NM_001352191, NM_001352192, NM_001352193, NM_001352194, NM_001352195, NM_001352196, NM_001352197, NM_001352198, NM_001352199, NM_001352200, NM_001352201, NM_001352202, NM_001352203, NM_001352204, NM_001352205, NM_001352206, NM_001352207, NM_001352208, NM_001352209, NM_001352210, NM_001352211, NM_001352212, NM_001352213, NM_001352214, NM_001352216, NM_001352217, NM_001352218, NM_001352219, NM_001352220, NM_001352221, NM_001352222, NM_001352223, NM_001352224, NM_001352225
Synonyms	AIDA; AIDA-1; ANKS2; cajalin-2; EB-1; EB1
Summary	This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]

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