Human TCEAL7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TCEAL7
Locus ID	56849
Kit Components	GA111233G1, TCEAL7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111233G2, TCEAL7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111233G3, TCEAL7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_152278, NM_001348258
Synonyms	MPMGp800C04260Q003; WEX5
Summary	Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.[UniProtKB/Swiss-Prot Function]

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