Human ASAH2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ASAH2
Locus ID	56624
Kit Components	GA111201G1, ASAH2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111201G2, ASAH2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111201G3, ASAH2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001143974, NM_019893
Synonyms	BCDase; HNAC1; LCDase; N-CDase; NCDase
Summary	Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008]

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