Human KCNQ5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KCNQ5
Locus ID	56479
Kit Components	GA111192G1, KCNQ5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111192G2, KCNQ5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111192G3, KCNQ5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001160130, NM_001160132, NM_001160133, NM_001160134, NM_019842
Synonyms	Kv7.5
Summary	This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

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