Human GSDMC activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GSDMC
Locus ID	56169
Kit Components	GA111150G1, GSDMC gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111150G2, GSDMC gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111150G3, GSDMC gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_031415
Synonyms	MLZE
Summary	The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable).[UniProtKB/Swiss-Prot Function]

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