Human C19orf61 (SMG9) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SMG9
Locus ID	56006
Kit Components	GA111088G1, C19orf61 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111088G2, C19orf61 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111088G3, C19orf61 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019108
Synonyms	C19orf61; F17127_1; HBMS
Summary	This gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense-mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features. [provided by RefSeq, Jul 2016]

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