Human Acetyl CoA synthetase (ACSS2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ACSS2
Locus ID	55902
Kit Components	GA111050G1, Acetyl CoA synthetase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111050G2, Acetyl CoA synthetase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111050G3, Acetyl CoA synthetase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001076552, NM_001242393, NM_018677, NM_139274, NR_028046
Synonyms	ACAS2; ACECS; ACS; ACSA; dJ1161H23.1
Summary	This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

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