Human HDAC8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HDAC8
Locus ID	55869
Kit Components	GA111031G1, HDAC8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111031G2, HDAC8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111031G3, HDAC8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166418, NM_001166419, NM_001166420, NM_001166422, NM_001166448, NM_018486, NR_051952
Synonyms	CDA07; CDLS5; HD8; HDACL1; MRXS6; RPD3; WTS
Summary	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

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