Human C9ORF46 (PLGRKT) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLGRKT
Locus ID	55848
Kit Components	GA111017G1, C9ORF46 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111017G2, C9ORF46 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111017G3, C9ORF46 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018465
Synonyms	AD025; C9orf46; MDS030; Plg-R(KT); PLG-RKT
Summary	Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9.[UniProtKB/Swiss-Prot Function]

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