Human TAF3B1 (BDP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BDP1
Locus ID	55814
Kit Components	GA110992G1, TAF3B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110992G2, TAF3B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110992G3, TAF3B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018429
Synonyms	HSA238520; TAF3B1; TFC5; TFIIIB; TFIIIB90; TFIIIB150; TFNR
Summary	The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. [provided by RefSeq, Jul 2008]

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