Human ST6GALNAC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ST6GALNAC1
Locus ID	55808
Kit Components	GA110986G1, ST6GALNAC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110986G2, ST6GALNAC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110986G3, ST6GALNAC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289107, NM_018414, NR_110309
Synonyms	HSY11339; SIAT7A; ST6GalNAcI; STYI
Summary	Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM, Mar 2008]

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