Human FRMD4A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FRMD4A
Locus ID	55691
Kit Components	GA110886G1, FRMD4A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110886G2, FRMD4A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110886G3, FRMD4A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001318336, NM_001318337, NM_001318338, NM_018027, NR_134578
Synonyms	bA295P9.4; CCAFCA; FRMD4
Summary	This gene encodes a FERM domain-containing protein that regulates epithelial cell polarity. It connects ADP ribosylation factor 6 (ARF6) with the Par protein complex, which regulates the remodeling of adherens junctions and linear actin cable formation during epithelial cell polarization. Polymorphisms in this gene are associated with Alzheimer's disease, and also with nicotine dependence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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