Human LIMS2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LIMS2
Locus ID	55679
Kit Components	GA110877G1, LIMS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110877G2, LIMS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110877G3, LIMS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001136037, NM_001161403, NM_001161404, NM_001256542, NM_017980, NR_027823
Synonyms	LGMD2W; PINCH-2; PINCH2
Summary	This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

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