Human DENND4C activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DENND4C
Locus ID	55667
Kit Components	GA110869G1, DENND4C gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110869G2, DENND4C gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110869G3, DENND4C gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001330640, NM_017925, NR_073201
Synonyms	bA513M16.3; C9orf55; C9orf55B; RAB10GEF
Summary	Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.[UniProtKB/Swiss-Prot Function]

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