Human FLVCR2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FLVCR2
Locus ID	55640
Kit Components	GA110847G1, FLVCR2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110847G2, FLVCR2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110847G3, FLVCR2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001195283, NM_017791
Synonyms	C14orf58; CCT; EPV; FLVCRL14q; MFSD7C; PVHH
Summary	This gene encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Aug 2010]

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