Human ZDHHC7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZDHHC7
Locus ID	55625
Kit Components	GA110834G1, ZDHHC7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110834G2, ZDHHC7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110834G3, ZDHHC7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001145548, NM_017740
Synonyms	DHHC7; SERZ-B; SERZ1; ZNF370
Summary	Palmitoyltransferase with broad specificity (PubMed:22031296, PubMed:28196865). Palmitoylates JAM3 (PubMed:28196865). Palmitoylates SNAP25 and DLG4/PSD95 (By similarity). Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane and their function in rapid intracellular signaling upon binding of sex hormones (PubMed:22031296). May play a role in follicle stimulation hormone (FSH) activation of testicular Sertoli cells (By similarity).[UniProtKB/Swiss-Prot Function]

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