Human DOCK10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DOCK10
Locus ID	55619
Kit Components	GA110828G1, DOCK10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110828G2, DOCK10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110828G3, DOCK10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290263, NM_014689, NM_017718, NM_001363762
Synonyms	DRIP2; Nbla10300; ZIZ3
Summary	This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2014]

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