Human TRPV6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRPV6
Locus ID	55503
Kit Components	GA110762G1, TRPV6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110762G2, TRPV6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110762G3, TRPV6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_014274, NM_018646
Synonyms	ABP/ZF; CAT1; CATL; ECAC2; HSA277909; LP6728; ZFAB
Summary	This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds. [provided by RefSeq, Feb 2015]

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