Human TBC1D2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TBC1D2
Locus ID	55357
Kit Components	GA110734G1, TBC1D2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110734G2, TBC1D2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110734G3, TBC1D2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001267571, NM_001267572, NM_018421, NR_051978
Synonyms	PARIS-1; PARIS1; TBC1D2A
Summary	Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.[UniProtKB/Swiss-Prot Function]

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