Human NEI3 (NEIL3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NEIL3
Locus ID	55247
Kit Components	GA110640G1, NEI3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110640G2, NEI3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110640G3, NEI3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018248
Synonyms	FGP2; FPG2; hFPG2; hNEI3; NEI3; ZGRF3
Summary	NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]

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