Human EXD2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EXD2
Locus ID	55218
Kit Components	GA110616G1, EXD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110616G2, EXD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110616G3, EXD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001193360, NM_001193361, NM_001193362, NM_001193363, NM_018199, NR_034164, NR_034165
Synonyms	C14orf114; EXDL2
Summary	Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.[UniProtKB/Swiss-Prot Function]

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