Human CLLD7 (RCBTB1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RCBTB1
Locus ID	55213
Kit Components	GA110611G1, CLLD7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110611G2, CLLD7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110611G3, CLLD7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018191, NM_001352500, NM_001352501, NM_001352502, NM_001352503, NM_001352504, NM_001352505, NM_001352506, NR_148015, NR_148016
Synonyms	CLLD7; CLLL7; GLP
Summary	This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008]

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