Human C14orf130 (UBR7) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UBR7
Locus ID	55148
Kit Components	GA110553G1, C14orf130 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110553G2, C14orf130 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110553G3, C14orf130 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001100417, NM_018108, NM_175748, NR_038150
Synonyms	C14orf130; FLJ10483; MGC9518
Summary	This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome. [provided by RefSeq, Jul 2016]

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