Human RADX activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RADX
Locus ID	55086
Kit Components	GA110504G1, RADX gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110504G2, RADX gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110504G3, RADX gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001184782, NM_018015
Synonyms	RP11-647M7.1
Summary	Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability (PubMed:28735897). Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks (PubMed:28735897).[UniProtKB/Swiss-Prot Function]

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