Human ZWILCH activation kit by CRISPRa
CAT#: GA110482
ZWILCH CRISPRa kit - CRISPR gene activation of human zwilch kinetochore protein
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | ZWILCH |
Locus ID | 55055 |
Kit Components | GA110482G1, ZWILCH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110482G2, ZWILCH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110482G3, ZWILCH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_001287821, NM_001287822, NM_001287823, NM_017975, NR_003105 |
Synonyms | hZwilch; KNTC1AP |
Summary | Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:15824131).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN413970 | ZWILCH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |