Human ATG16L1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ATG16L1
Locus ID	55054
Kit Components	GA110481G1, ATG16L1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110481G2, ATG16L1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110481G3, ATG16L1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001190266, NM_001190267, NM_017974, NM_030803, NM_198890, NM_001363742
Synonyms	APG16L; ATG16A; ATG16L; IBD10; WDR30
Summary	The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]

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