Human C1orf56 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	C1orf56
Locus ID	54964
Kit Components	GA110410G1, C1orf56 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110410G2, C1orf56 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110410G3, C1orf56 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_017860
Synonyms	MENT
Summary	This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene. [provided by RefSeq, Sep 2016]

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