Human RNF125 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RNF125
Locus ID	54941
Kit Components	GA110390G1, RNF125 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110390G2, RNF125 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110390G3, RNF125 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_017831
Synonyms	TNORS; TRAC-1; TRAC1
Summary	This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012]

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