Human NSUN2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NSUN2
Locus ID	54888
Kit Components	GA110345G1, NSUN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110345G2, NSUN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110345G3, NSUN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001193455, NM_017755, NR_037947
Synonyms	MISU; MRT5; SAKI; TRM4
Summary	This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011]

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