Human TEX10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TEX10
Locus ID	54881
Kit Components	GA110338G1, TEX10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110338G2, TEX10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110338G3, TEX10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001161584, NM_017746
Synonyms	bA208F1.2; Ipi1
Summary	Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (PubMed:21326211).[UniProtKB/Swiss-Prot Function]

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