Human PIGG activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PIGG
Locus ID	54872
Kit Components	GA110329G1, PIGG gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110329G2, PIGG gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110329G3, PIGG gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001127178, NM_001289051, NM_001289052, NM_001289053, NM_001289055, NM_001289057, NM_001345986, NM_001345987, NM_001345988, NM_001345989, NM_001345990, NM_001345991, NM_001345994, NM_017733, NR_110293, NR_144326, NR_144327, NR_144328, NR_144329, NR_144330, NR_144331, NR_144332, NR_144333, NR_144334
Synonyms	GPI7; LAS21; MRT53; PRO4405; RLGS1930
Summary	This gene encodes an enzyme involved in glycosylphosphatidylinositol-anchor biosynthesis. The encoded protein, which is localized to the endoplasmic reticulum, is involved in transferring ethanoloamine phosphate to mannose 2 of glycosylphosphatidylinositol species H7 to form species H8. Allelic variants of this gene have been associated with intellectual disability, hypotonia, and early-onset seizures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

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