Human Dymeclin (DYM) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DYM
Locus ID	54808
Kit Components	GA110275G1, Dymeclin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110275G2, Dymeclin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110275G3, Dymeclin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_017653, NM_001353210, NM_001353211, NM_001353212, NM_001353213, NM_001353214, NM_001353215, NM_001353216
Synonyms	DMC; SMC
Summary	This gene encodes a protein which regulates Golgi-associated secretory pathways that are essential to endochondral bone formation during early development. This gene is also believed to play a role in early brain development. This gene is widely expressed in embryos and is particularly abundant in chodrocytes and brain tissues. It encodes a peripheral membrane protein which shuttles between the cytosol and Golgi complex. Mutations in this gene are associated with two types of recessive osteochondrodysplasia: Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia. [provided by RefSeq, Jun 2017]

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