Human LEPROT activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LEPROT
Locus ID	54741
Kit Components	GA110237G1, LEPROT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110237G2, LEPROT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110237G3, LEPROT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001198681, NM_001198683, NM_017526
Synonyms	LEPR; OB-RGRP; OBRGRP; VPS55
Summary	LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]).[supplied by OMIM, Jul 2010]

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