Human XAF1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	XAF1
Locus ID	54739
Kit Components	GA110236G1, XAF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110236G2, XAF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110236G3, XAF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_017523, NM_199139, NR_046396, NR_046397, NR_046398, NM_001353134, NM_001353135, NM_001353136, NM_001353137, NM_001353138, NM_001353139, NM_001353140
Synonyms	BIRC4BP; HSXIAPAF1; XIAPAF1
Summary	This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

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