Human WDR74 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WDR74
Locus ID	54663
Kit Components	GA110212G1, WDR74 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110212G2, WDR74 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110212G3, WDR74 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001307977, NM_018093, NM_001369447, NM_001369453, NR_161381, NM_001369448, NM_001369449, NM_001369450, NM_001369451
Summary	Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit (PubMed:26456651). Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (PubMed:29107693). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (By similarity).[UniProtKB/Swiss-Prot Function]

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