Human INO80 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	INO80
Locus ID	54617
Kit Components	GA110198G1, INO80 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110198G2, INO80 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110198G3, INO80 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_017553, NM_032196, NR_104038
Synonyms	hINO80; INO80A; INOC1
Summary	This gene encodes a subunit of the chromatin remodeling complex, which is classified into subfamilies depending on sequence features apart from the conserved ATPase domain. This protein is the catalytic ATPase subunit of the INO80 chromatin remodeling complex, which is characterized by a DNA-binding domain. This protein is proposed to bind DNA and be recruited by the YY1 transcription factor to activate certain genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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