Human EXOC6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EXOC6
Locus ID	54536
Kit Components	GA110162G1, EXOC6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110162G2, EXOC6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110162G3, EXOC6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001013848, NM_001319194, NM_001319195, NM_001319200, NM_019053
Synonyms	EXOC6A; SEC15; SEC15L; SEC15L1; SEC15L3; Sec15p
Summary	The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product, which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA). Alternative splicing and the use of alternative promoters results in multiple transcript variants. A paralogous gene encoding a similar protein is present on chromosome 2. [provided by RefSeq, Jan 2016]

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